Can vitamins help kidneys work better?
A Pilot Trial of Nicotinamide Riboside and Coenzyme Q10 on Inflammation and Oxidative Stress in CKD
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
NR increased IL-2, a pro-inflammatory cytokine, while still reducing overall oxidative stress.
Most expect anti-aging supplements to reduce all inflammation, but IL-2 is involved in immune regulation—this could mean NR is fine-tuning immunity, not just suppressing it.
Practical Takeaways
People with moderate-to-severe kidney disease might consider NR or CoQ10 under medical supervision to reduce oxidative stress.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
NR increased IL-2, a pro-inflammatory cytokine, while still reducing overall oxidative stress.
Most expect anti-aging supplements to reduce all inflammation, but IL-2 is involved in immune regulation—this could mean NR is fine-tuning immunity, not just suppressing it.
Practical Takeaways
People with moderate-to-severe kidney disease might consider NR or CoQ10 under medical supervision to reduce oxidative stress.
Publication
Journal
Clinical Journal of the American Society of Nephrology : CJASN
Year
2025
Authors
A. Ahmadi, A. P. Valencia, G. Begue, J. Norman, Sili Fan, Blythe P. Durbin-Johnson, Bradley N Jenner, Matthew D. Campbell, Gustavo Reyes, Pankaj Kapahi, Jonathan Himmelfarb, I. D. de Boer, D. Marcinek, Bryan R. Kestenbaum, Jorge L. Gamboa, B. Roshanravan
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Claims (7)
Keeping energy levels healthy in hair cells helps protect the cells that give hair its color, so they don’t die off too soon.
Taking 1200 mg of CoQ10 every day for six weeks might help reduce harmful stress in the body for adults with moderate to severe kidney disease.
Taking a supplement called nicotinamide riboside for six weeks might help immune cells in people with kidney disease work better by boosting their energy levels.
Taking a supplement called nicotinamide riboside every day for six weeks might help reduce harmful stress in the body for adults with moderate to severe kidney disease.
Taking a supplement called nicotinamide riboside for six weeks might change how genes work in the blood of people with moderate to severe kidney disease, possibly affecting how the body handles sugar, fat, and the immune system.