Taking a supplement called nicotinamide riboside every day for six weeks might boost a protein in the blood that affects the immune system in people with moderate to severe kidney disease — but we...

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Randomized Crossover Clinical Trial of Nicotinamide Riboside and Coenzyme Q10 on Metabolic Health and Mitochondrial Bioenergetics in CKD

Randomized Controlled Trial

Human

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Randomized Crossover Clinical Trial of Nicotinamide Riboside and Coenzyme Q10 on Metabolic Health and Mitochondrial Bioenergetics in CKD

Score: 72

DOI: 10.1101/2024.08.23.24312501

Similar Assertions

Taking a supplement called nicotinamide riboside for six weeks might change how genes work in the blood of people with moderate to severe kidney disease, possibly affecting how the body handles sugar, fat, and the immune system.

83%

Taking a supplement called nicotinamide riboside for six weeks might change how certain genes work in people with moderate to severe kidney disease, possibly helping with energy and metabolism.

82%

In people with moderate to severe kidney disease, taking 1000 mg of nicotinamide riboside daily for six weeks may boost energy in immune cells, but the same doesn’t happen with a high dose of CoQ10.

80%

Taking a supplement called nicotinamide riboside for six weeks might help immune cells in people with serious kidney disease work better by boosting their energy levels.

79%

Taking a supplement called nicotinamide riboside every day for six weeks might help reduce harmful stress in the body for adults with moderate to severe kidney disease.

79%