Can vitamins help kidney disease by fixing cell energy and reducing damage?
Randomized Crossover Clinical Trial of Nicotinamide Riboside and Coenzyme Q10 on Metabolic Health and Mitochondrial Bioenergetics in CKD
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some people with kidney disease took special vitamins (NR or CoQ10) for six weeks to see if they helped their cells work better and reduced damage from stress and swelling.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 572 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some people with kidney disease took special vitamins (NR or CoQ10) for six weeks to see if they helped their cells work better and reduced damage from stress and swelling.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 572 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
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Claims (6)
Taking a supplement called nicotinamide riboside every day for six weeks might boost a protein in the blood that affects the immune system in people with moderate to severe kidney disease — but we don’t know yet if that change actually helps or matters for their health.
In people with moderate to severe kidney disease, taking either nicotinamide riboside or coenzyme Q10 for six weeks seems to change how certain genes work in the blood — one affects energy and fat processing, while the other influences immunity and stress, suggesting they work in different ways.
Taking certain supplements like nicotinamide riboside or CoQ10 for six weeks might help reduce harmful stress in the body for people with moderate to severe kidney disease.
In people with moderate to severe kidney disease, taking 1000 mg of nicotinamide riboside daily for six weeks may boost energy in immune cells, but the same doesn’t happen with a high dose of CoQ10.
Taking 1200 mg of CoQ10 every day for six weeks might help lower two key markers of inflammation in people with moderate to severe kidney disease, even though one of the markers didn’t stay significant when checked more strictly.