Researchers measured blood pressure and nitrate/nitrite levels in blood and saliva 2.5 hours after giving women a nitrate-rich drink.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study describes the measurement timing without making causal claims. The language 'were determined 2.5 hours later' appropriately describes the study procedure.

Evidence from Studies

Supporting (1)

Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation

Cross-Sectional Study

Human

2023 Nov

Contradicting (0)

No contradicting evidence found

Source Study

Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation

Score: 34

DOI: 10.1161/HYPERTENSIONAHA.123.21263

Similar Assertions

When nitrite levels in the blood go up after taking nitrate supplements, blood pressure tends to go down more. The higher the nitrite increase, the bigger the blood pressure drop.

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When nitrite levels in the blood went down after using mouthwash, blood pressure went up, and this connection was strong enough to be statistically significant.

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When bacteria that help convert nitrate to nitrite in the mouth are reduced, blood pressure tends to go up by a small amount (2-3.5 mmHg for systolic and 2-2.2 mmHg for diastolic).

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Using a special mouthwash for a week killed some good bacteria in the mouth, which made less nitrite in saliva and blood, and this caused blood pressure to go up a little bit.

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Even when people ate a diet low in nitrate, using the special mouthwash still increased their blood pressure, which suggests the effect comes from the body's own nitrate recycling process.

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