Scientists found chemical compounds in the calyces of the Bombax ceiba plant that are known to reduce blood sugar, stimulate insulin release, and reduce oxidative stress, and these compounds may...
Mechanism
Synthesis from 1 study
The flower parts of Bombax ceiba contain natural chemicals that enter the blood and tell the pancreas to release more insulin. These chemicals also help muscle and liver cells pull sugar out of the blood more effectively, which brings blood sugar down. No other ways this might work were shown in...
Most probable mechanism
Natural chemicals in the flower parts of Bombax ceiba enter the bloodstream, signal the pancreas to release more insulin, and help muscle and liver cells take up sugar from the blood more efficiently, which lowers blood sugar levels.
Bioactive phytometabolites (e.g., flavonoids and phenolic acids) are absorbed from the gastrointestinal tract into systemic circulation
These compounds bind to receptors on pancreatic beta-cells, triggering calcium influx and stimulating insulin secretion
Insulin signaling pathways (IRS-1/PI3K/Akt) are activated in skeletal muscle and liver tissues
GLUT4 glucose transporters move to the cell membrane in insulin-sensitive tissues, increasing glucose uptake from the blood
Evidence from Studies
Supporting (1)
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