If you're an adult with extra weight but don't have diabetes, taking a weekly 2.4 mg shot of semaglutide for about a year and a half can help you lose around 13 kg of fat, including some deep belly fat, while mostly keeping your muscle — even though you might lose a little muscle too, the fat loss is much bigger.

For adults who aren't diabetic but carry extra weight, a weekly injection of semaglutide (2.4 mg) plus healthy lifestyle changes led to nearly 15% weight loss over a year and a half—way more than lifestyle changes alone.

Taking a weekly injection called semaglutide along with healthy eating and exercise can help people with obesity or overweight lose about 15% of their body weight in a year—much more than people who just take a sugar pill.

Taking a weekly shot called semaglutide 2.4 mg helps people who are overweight and have prediabetes lose a lot of weight—about 15 kg in a year—and even after stopping the shot, they still keep off nearly 9 kg. This also helps stop them from developing full-blown diabetes.

In a group of 32 people with type 2 diabetes, taking oral semaglutide for 6 months led to a noticeable drop in body fat, with an average loss of about 17.6% of their initial fat mass.

People with obesity and another health issue who got a weekly shot of semaglutide plus behavioral therapy lost about 17 kg on average after a year and a half — way more than those who got a placebo.