Sesame seeds might help your body process estrogen in a safer way, making more of the good kinds and less of the bad kinds that could cause problems.
Evidence from Studies
Supporting (1)
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The study looked at a supplement with a type of lignan similar to those in sesame seeds and found it helped the body process estrogen in a safer way, which supports the idea that sesame lignans could do the same.
Contradicting (1)
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Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors
The study found that sesame seeds made cancer tumors less responsive to treatment in mice, which goes against the idea that they help the body produce safer forms of estrogen.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.