Skin cells around the hair follicle make WNT signals that turn on WNT activity in pigment stem cells in mice.

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Community contributions welcome

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Dedifferentiation maintains melanocyte stem cells in a dynamic niche

Cohort Study

Animal

2023 Apr

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No contradicting evidence found

WNT signals in the hair follicle are linked to pigment cells turning into mature color-producing cells in mice.

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96%

Mouse hair pigment cells move between different parts of the hair follicle and change their state back and forth, which is linked to WNT signaling.

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90%

When mouse hair starts growing, pigment stem cells in the hair germ turn on color-making and branch-related genes before they divide.

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71%