The Claim

In healthy young adults, supplementation with 10 g/day of creatine for 6 weeks was associated with a trend toward reduced prefrontal cortex oxyhemoglobin (O2Hb) during processing speed tasks (p=0.06), suggesting a possible shift toward more efficient cerebral energy utilization, though the finding was not statistically significant.

Source: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
53score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In healthy young adults, taking 10 grams of creatine daily for six weeks was linked to a small, non-significant decrease in oxygen levels in the prefrontal cortex during tasks requiring quick thinking, which may indicate a change in how the brain uses energy.

See the scientific wording

A trend toward reduced prefrontal cortex oxyhemoglobin (O2Hb) during processing speed tasks was observed in healthy young adults taking 10 g/day of creatine for 6 weeks (p=0.06), suggesting a possible shift toward more efficient cerebral energy utilization, though this finding was not statistically significant and requires replication.

What the research says

1 study
  1. Study: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults

    This study found that people who took 10 grams of creatine daily for six weeks showed a slight hint that their brains might be working more efficiently during fast-thinking tasks, even though the result wasn’t strong enough to be certain. It doesn’t prove it, but it doesn’t contradict it either.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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