Some proteins found in beans and wheat may increase leakage in the gut lining and trigger inflammation in laboratory models, which could potentially lead to autoimmune reactions via specific biological pathways involving molecular mimicry and the NLRP3 inflammasome.

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From inflammation to immune regulation: The dual nature of dietary lectins in health and disease

Narrative Review

2024 Oct 30

Some beans and wheat contain proteins called lectins that can irritate the gut and trigger inflammation, which might confuse the immune system and lead to autoimmune problems — and this study says that’s true for certain lectins like those in kidney beans.

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Source Study

From inflammation to immune regulation: The dual nature of dietary lectins in health and disease

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DOI: 10.1016/j.heliyon.2024.e39471

Similar Assertions

Lectins are plant-derived proteins that can translocate across the intestinal barrier, bind to mammalian tissues, and trigger inflammatory or autoimmune responses in susceptible individuals.

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Certain antibodies produced in response to proteins in wheat may bind to human proteins found in the thyroid, muscles, and other tissues, which could potentially trigger immune responses against the body's own tissues in some individuals.

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