The Claim

Sulforaphane supplementation at 120 μmol/day for 12 months does not significantly alter Caspase-3 or TUNEL apoptotic marker levels in bronchial tissue of former smokers.

Source: Abstract 749: Randomized placebo-controlled phase II clinical trial on oral supplementation of sulforaphane for 12 months that reduced bronchial Ki-67 index in former smokers at high risk for lung cancer

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
61score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

Taking 120 micromoles of sulforaphane daily for a year does not change levels of Caspase-3 or TUNEL markers in the bronchial tissue of former smokers.

See the scientific wording

Sulforaphane supplementation at 120 μmol/day for 12 months had no significant effect on Caspase-3 or TUNEL apoptotic markers in bronchial tissue of former smokers, indicating that its anti-proliferative effect is not mediated through increased apoptosis in this context.

Why this might work

Sulforaphane enters lung cells and turns on a protective system that cleans up harmful chemicals from smoking. This reduces damage to DNA, which stops the cells from dividing too fast. The cells do not die off more than usual; they just stop multiplying.

Supported mechanismbased on 1 study

What the research says

1 study

  1. Study: Abstract 749: Randomized placebo-controlled phase II clinical trial on oral supplementation of sulforaphane for 12 months that reduced bronchial Ki-67 index in former smokers at high risk for lung cancer

    Sulforaphane helped slow down abnormal cell growth in the lungs of former smokers, but it didn’t make those bad cells die faster — which means it works by stopping them from multiplying, not by killing them off.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.