The Claim

Daily oral supplementation with 120 μmol of sulforaphane for 12 months reduced the Ki-67 proliferation index by 24% in bronchial tissue of former smokers with at least 30 pack-years of smoking history.

Source: Abstract 749: Randomized placebo-controlled phase II clinical trial on oral supplementation of sulforaphane for 12 months that reduced bronchial Ki-67 index in former smokers at high risk for lung cancer

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
61score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

Taking 120 micromoles of sulforaphane daily for one year reduced the Ki-67 proliferation index by 24% in bronchial tissue of former smokers with a 30 pack-year smoking history.

See the scientific wording

Daily oral supplementation with 120 μmol of sulforaphane for 12 months significantly reduced the Ki-67 proliferation index by 24% in bronchial tissue of former smokers with at least 30 pack-years of smoking history, suggesting a biological effect on cellular proliferation in high-risk individuals.

Why this might work

Sulforaphane enters cells in the airways and turns on a natural defense system that cleans up harmful chemicals from smoking. This reduces damage to DNA, which stops cells from dividing too quickly.

Supported mechanismbased on 1 study

What the research says

1 study

  1. Study: Abstract 749: Randomized placebo-controlled phase II clinical trial on oral supplementation of sulforaphane for 12 months that reduced bronchial Ki-67 index in former smokers at high risk for lung cancer

    Scientists gave former heavy smokers a daily supplement made from broccoli seeds for a year, and found that the number of rapidly dividing cells in their airways went down—this is a good sign it might help prevent lung cancer.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.