The Claim

In postmenopausal women aged 45–85, daily supplementation with 150 mg of trans-resveratrol for 24 months significantly increased resting mean cerebral blood flow velocity by 27.5% (Cohen’s d = 0.275, P = 0.001) and improved cerebrovascular responsiveness to both hypercapnia and cognitive stimuli.

Source: Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
57score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

In postmenopausal women aged 45–85, taking 150 mg of trans-resveratrol daily for 24 months increased blood flow velocity in the brain by 27.5% and improved the brain's blood vessel response to carbon dioxide and mental tasks.

See the scientific wording

In postmenopausal women aged 45–85, daily supplementation with 150 mg of trans-resveratrol for 24 months significantly increased resting mean cerebral blood flow velocity by 27.5% (Cohen’s d = 0.275, P = 0.001) and improved cerebrovascular responsiveness to both hypercapnia and cognitive stimuli, indicating enhanced blood flow regulation in the brain.

Why this might work

Resveratrol turns on a protein called SIRT1, which activates an enzyme that makes nitric oxide. Nitric oxide tells blood vessels in the brain to relax, allowing more blood to flow through. This increases blood flow at rest and improves the brain's ability to respond when it needs more oxygen, such as during thinking or when carbon dioxide levels rise.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study.

    This study found that taking 150 mg of resveratrol every day for two years helped older women’s brains get more blood flow and respond better to changes like holding their breath or thinking hard — just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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