The Claim

Daily supplementation with 150 mg of trans-resveratrol for 24 months significantly reduced fasting insulin levels by 17.4% and improved the insulin resistance index in postmenopausal women aged 45–85.

Source: Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
57score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

In postmenopausal women aged 45–85, taking 150 mg of trans-resveratrol daily for two years lowered fasting insulin levels by 17.4% and improved the insulin resistance index.

See the scientific wording

In postmenopausal women aged 45–85, daily supplementation with 150 mg of trans-resveratrol for 24 months significantly reduced fasting insulin levels by 17.4% (Cohen’s d = 0.174, P = 0.025) and improved insulin resistance index (Cohen’s d = 0.102, P = 0.034), indicating enhanced insulin sensitivity.

Why this might work

Resveratrol turns on two key cellular sensors, SIRT1 and AMPK, which signal muscle and fat cells to pull more sugar from the blood. This lowers the amount of insulin the body needs to produce to keep blood sugar stable.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study.

    This study gave postmenopausal women 150 mg of resveratrol every day for two years and found their insulin levels dropped by 17.4%, meaning their bodies handled sugar better. This matches exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.