Taking 25 mg of prednisolone daily for five days reduces the natural daily fluctuations in the activity of key clock genes in muscle and fat tissue, suggesting the drug directly interferes with the...

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Evidence from Studies

Supporting (1)

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Effects of prednisolone administration on clock gene expression and indices of circadian rhythms in healthy human males.

Randomized Controlled Trial

Human

2026 Mar 17

Contradicting (0)

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No contradicting evidence found

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Source Study

Effects of prednisolone administration on clock gene expression and indices of circadian rhythms in healthy human males.

Score: 62

DOI: 10.1210/clinem/dgaf564

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