The Claim

An 8-gram daily loading dose of citrulline malate administered over four days has no significant effect on muscular endurance during individual sets, maximal isometric, concentric, or eccentric strength, rate of force development, or muscle soreness in resistance-trained males.

Source: The Acute Effect of Citrulline Malate Loading in Resistance Trained Males on: Anaerobic Muscular Endurance, Force Recovery and Muscle Soreness

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
52score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

Taking 8 grams of citrulline malate per day for four days does not change muscular endurance, maximum strength in different types of muscle contractions, how quickly force is generated, or muscle soreness in men who regularly train with weights.

See the scientific wording

An 8-gram daily loading dose of citrulline malate over four days does not significantly improve muscular endurance during individual sets, maximal isometric, concentric, or eccentric strength, rate of force development, or muscle soreness in resistance-trained males.

Why this might work

The body breaks down citrulline malate into citrulline and malate, but after four days of 8 grams per day, this does not increase nitric oxide production or improve how muscles use energy during intense exercise, so strength, endurance, and recovery stay the same.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: The Acute Effect of Citrulline Malate Loading in Resistance Trained Males on: Anaerobic Muscular Endurance, Force Recovery and Muscle Soreness

    The study found that taking 8 grams of citrulline malate for four days didn’t help men lift more reps per set, get stronger, recover faster, or feel less sore — which is exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.