The Claim

An 8-gram daily loading dose of citrulline malate administered over four days increases the total number of repetitions performed during a German Volume Training protocol by approximately 13% (68.1 vs. 54.9 repetitions) in resistance-trained males, but does not improve muscular endurance across individual sets, strength, force recovery, or muscle soreness.

Source: The Acute Effect of Citrulline Malate Loading in Resistance Trained Males on: Anaerobic Muscular Endurance, Force Recovery and Muscle Soreness

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
52score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Taking 8 grams of citrulline malate daily for four days increases the total number of repetitions performed in a German Volume Training workout by about 13% in trained men, but does not improve endurance within individual sets, strength, force recovery, or reduce muscle soreness.

See the scientific wording

An 8-gram daily loading dose of citrulline malate over four days increases the total number of repetitions performed during a German Volume Training protocol by approximately 13% (68.1 vs. 54.9 repetitions) in resistance-trained males, but does not improve muscular endurance across individual sets, strength, force recovery, or muscle soreness.

Why this might work

Citrulline malate helps the body remove ammonia faster and reduces muscle acidity during intense workouts, allowing muscles to keep working longer without fatiguing as quickly.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: The Acute Effect of Citrulline Malate Loading in Resistance Trained Males on: Anaerobic Muscular Endurance, Force Recovery and Muscle Soreness

    Taking 8 grams of citrulline malate for four days helped men do about 13 more total reps in a tough workout, but didn’t make them stronger, less sore, or able to do more reps in each individual set — just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.