Daily supplementation with 100 mg of standardized Asparagus racemosus root extract (CL22209) for 84 days significantly increases serum FSH and sex hormone-binding globulin, decreases the LH:FSH ratio, and reduces total testosterone compared to placebo in women with polycystic ovary syndrome, indicating a favorable shift in hormonal balance.

This plant extract works like a gentle hormone balancer. It fits into locks in the brain's hormone control center, changing the signals that tell the ovaries to work. This makes the brain release more FSH and less LH. Lower LH tells the ovaries to make less testosterone. At the same time, the extract makes the body more responsive to insulin, so blood insulin goes down. Low insulin causes the liver to make more SHBG, a protein that attaches to testosterone and clears it from the blood. With less free testosterone and a healthier FSH-LH balance, the ovaries can release eggs normally, unwanted hair and acne fade, and menstrual cycles become regular.