The Claim

Daily administration of 100 mg enteric-coated aspirin does not significantly reduce the incidence of major adverse cardiovascular events, including fatal coronary heart disease, nonfatal myocardial infarction, or fatal or nonfatal ischemic stroke, in healthy community-dwelling adults aged 70 years and older.

Source: Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
88score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Taking a daily 100 mg aspirin pill does not actually lower the risk of serious heart problems or strokes in healthy seniors over 70. A recent study showed that older adults who took aspirin had almost the same rate of heart events as those who took a placebo.

See the scientific wording

Daily administration of 100 mg enteric-coated aspirin does not significantly reduce the rate of major adverse cardiovascular events, defined as fatal coronary heart disease, nonfatal myocardial infarction, or fatal or nonfatal ischemic stroke, in healthy community-dwelling adults aged 70 years and older. Over a median follow-up of 4.7 years, the event rate was 7.8 per 1000 person-years in the aspirin group versus 8.8 per 1000 person-years in the placebo group, yielding a hazard ratio of 0.89 (95% CI 0.77 to 1.03), confirming the absence of a statistically significant protective effect against ischemic cardiovascular events in this demographic.

What the research says

1 study

  1. Study: Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

    The RCT evaluated this non-prespecified endpoint. The confidence interval crossing 1.0 and the lack of statistical significance indicate no causal reduction in ischemic cardiovascular events.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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