Does Daily Aspirin Protect Older Adults from Heart Problems?

Original Title

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

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Summary

Researchers tested if giving healthy people over 70 a daily low-dose aspirin pill prevents heart attacks and strokes. They found it didn't help prevent heart issues, but it did cause more serious bleeding, especially in the stomach and brain.

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Surprising Findings

The bleeding risk remained completely constant over time and did not wane with prolonged therapy.

Most medications see side effects peak early and then stabilize or decrease; aspirin's risk profile showed a steady, linear accumulation without physiological adaptation.

Practical Takeaways

If you're over 70 and healthy, talk to your doctor about stopping daily aspirin for heart prevention unless you have a specific medical reason.

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Publication

Journal

The New England Journal of Medicine

Year

2018

Authors

J. McNeil, R. Wolfe, R. Woods, A. Tonkin, G. Donnan, Mark R. Nelson, C. Reid, J. Lockery, B. Kirpach, E. Storey, R. Shah, J. Williamson, K. Margolis, M. Ernst, W. Abhayaratna, N. Stocks, S. Fitzgerald, S. Orchard, R. Trevaks, L. Beilin, C. Johnston, J. Ryan, B. Radziszewska, M. Jelinek, M. Malik, C. Eaton, D. Brauer, G. Cloud, E. Wood, S. Mahady, S. Satterfield, R. Grimm, A. Murray

Open Access
924 citations
Analysis v1

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