The Claim

Oral supplementation with 60 mg/day of a hyaluronic acid matrix for 12 weeks reduces skin roughness by 0.8 SEr units on the cheek and increases skin smoothness by 71 SEsm units on the periocular area in healthy women aged 35–65.

Source: Oral Supplementation with a New Hyaluronic Acid Matrix Ingredient Improves Skin Brightness, Hydration, Smoothness, and Roughness: Results from a Randomized, Double-Blinded, Placebo-Controlled Study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
76score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

Taking 60 mg of a hyaluronic acid supplement daily for 12 weeks reduces skin roughness on the cheeks and increases skin smoothness around the eyes in healthy women aged 35 to 65.

See the scientific wording

Oral supplementation with 60 mg/day of a hyaluronic acid matrix for 12 weeks significantly reduces skin roughness by 0.8 SEr units on the cheek and improves skin smoothness by 71 SEsm units on the periocular area in healthy women aged 35–65, indicating a measurable improvement in skin texture.

Why this might work

When taken by mouth, hyaluronic acid and related molecules are absorbed into the blood and reach the skin, where they signal skin cells to make more water-holding material and structural proteins. This increases moisture deep in the skin, which flows upward to the outer layer, making it smoother and less flaky. The improved structure also reduces redness and stabilizes the skin's natural acidity, which prevents irregular shedding of surface cells and enhances light reflection for a more even texture.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Oral Supplementation with a New Hyaluronic Acid Matrix Ingredient Improves Skin Brightness, Hydration, Smoothness, and Roughness: Results from a Randomized, Double-Blinded, Placebo-Controlled Study

    This study found that taking a daily pill with hyaluronic acid for 3 months made women’s skin feel smoother around the eyes and less rough on the cheeks, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.