Analysis Version
v1
History
Back to Study: A Pilot Trial of Nicotinamide Riboside and Coenzym...
correlational
Analysis v1
Strong Support

Taking 1200 mg of coenzyme Q10 every day for six weeks might help lower inflammation in adults with moderate to severe kidney disease.

72
Pro
0
Against

Evidence from Studies

Supporting (1)

72

Community contributions welcome

72

A Pilot Trial of Nicotinamide Riboside and Coenzyme Q10 on Inflammation and Oxidative Stress in CKD

Randomized Controlled Trial
Human
2025 Mar 1

The study gave people with kidney disease 1200 mg of CoQ10 daily for 6 weeks and found their inflammation marker (CRP) went down, which supports the idea that CoQ10 may help reduce inflammation.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

A Pilot Trial of Nicotinamide Riboside and Coenzyme Q10 on Inflammation and Oxidative Stress in CKD

Score: 72
DOI: 10.2215/CJN.0000000624

Similar Assertions

Taking 1200 mg of CoQ10 every day for six weeks might help lower two key markers of inflammation in people with moderate to severe kidney disease, even though one of the markers didn’t stay significant when checked more strictly.

72
0
96%

Taking a certain dose of CoQ10 every day for six weeks might help lower inflammation in people with moderate to severe kidney disease.

72
0
92%

Taking 1200 mg of CoQ10 every day for six weeks might help reduce harmful stress in the body for adults with moderate to severe kidney disease.

72
0
91%

Taking a certain dose of CoQ10 for six weeks might change how genes work in people with serious kidney disease, possibly helping with inflammation and metabolism.

72
0
87%

In people with moderate to severe kidney disease, taking either nicotinamide riboside or coenzyme Q10 for six weeks seems to change how certain genes work in the blood — one affects energy and fat processing, while the other influences immunity and stress, suggesting they work in different ways.

72
0
77%