Taking creatine while rebuilding leg strength after being inactive might help your muscles improve faster by boosting a key protein that helps with energy use.

Taking creatine every day while your leg is immobilized might help keep your muscles' ability to handle sugar working better, so they don’t weaken as much.

If you're a healthy young adult getting back into strength training after resting your leg for two weeks, taking creatine might give you more energy in your muscles and boost creatine levels after three weeks — but by ten weeks, that advantage goes away.

Taking creatine might help your muscles keep using sugar properly when you're not moving much, and help them rebuild faster when you start moving again.

Taking creatine supplements leads to higher levels of creatine in muscles, improves the ability to regenerate energy during intense workouts, and over 8 to 12 weeks, allows for more total training and measurable muscle growth.

Creatine helps muscles refill their energy stores quickly after a tough workout, but this boost only lasts the first day — even if you keep taking creatine, it doesn’t keep speeding things up after that.