The Claim
Oral creatine supplementation at a dose of 20 g per day for two weeks during leg immobilization helps maintain muscle GLUT4 protein content in healthy young adults, preventing the approximately 20% decline observed with placebo, indicating a supportive role of creatine in molecular mechanisms related to glucose transport during muscle disuse.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking creatine every day while your leg is immobilized might help keep your muscles' ability to handle sugar working better, so they don’t weaken as much.
See the scientific wording
Oral creatine supplementation at a dose of 20 g per day during 2 weeks of leg immobilization may help maintain muscle GLUT4 protein content in healthy young adults, preventing the approximately 20% decline observed with placebo, suggesting creatine supports molecular mechanisms related to glucose transport during muscle disuse.
What the research says
1 studyStudy: Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilization.
The study shows that taking creatine every day during two weeks of leg immobilization helped keep important muscle proteins (GLUT4) stable, while those who took a fake pill lost about 20% of these proteins.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.