Oral supplementation with either liposomal or nonliposomal formulations containing 50 mL/day of fish-derived collagen tripeptides, yeast extract, hyaluronic acid, and resveratrol for 8 weeks significantly increases dermal collagen density and skin hydration in healthy adults aged 25–65 compared to placebo.

When you swallow the supplement, the tiny fat bubbles protect the collagen pieces so they don't break down in your stomach. These protected pieces get absorbed into your blood, travel to your skin, and tell the skin cells to make more collagen and elastic fibers. At the same time, other ingredients in the supplement help the skin hold more water and build more of its natural moisturizing network, making the skin thicker and more hydrated.