For people with a genetic cholesterol problem who are already on cholesterol meds, taking a pill called enlicitide every day for a year keeps their bad cholesterol way down — cutting it by more than half — while those not taking it see their levels go up.

For adults with a genetic cholesterol problem and already taking statins, adding a pill called enlicitide every day for 6 months slashed bad cholesterol levels by over half, while a fake pill barely changed anything.

For adults with a genetic cholesterol problem who are already taking cholesterol pills, adding a daily 20 mg pill called enlicitide for 6 months cuts a harmful type of blood fat (lipoprotein(a)) by about a quarter—way more than a dummy pill does.

For people with a genetic cholesterol problem who are already on cholesterol pills, taking a new drug called enlicitide every day for 6 months might slash their bad cholesterol way more than just the usual treatment alone.

For adults with a genetic cholesterol problem who are already on cholesterol meds, taking a pill called enlicitide every day for 6 months might drastically lower a key heart disease risk protein in their blood.

For people at very high risk of heart problems, taking cholesterol-lowering drugs called statins plus another drug called ezetimibe lowers bad cholesterol more than taking statins alone — by about 13 points on average — and helps them hit their cholesterol targets better.