Taking cholesterol drugs called evolocumab or alirocumab doesn’t seem to raise your risk of bleeding in the brain — the numbers show it’s about the same as not taking them.

From: Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials.

Strongly supported

Multiple high-quality studies back this claim.

38
Pro
0
Against
quantitative
1 study

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What this claim means

Taking cholesterol drugs called evolocumab or alirocumab doesn’t seem to raise your risk of bleeding in the brain — the numbers show it’s about the same as not taking them.

See the technical phrasing

Treatment with the PCSK9 inhibitors evolocumab or alirocumab is not associated with a statistically significant difference in the risk of hemorrhagic stroke compared to control groups, with a relative risk of 1.041 (95% confidence interval: 0.690–1.573), indicating no detectable increase in bleeding-related brain events.

What the research says

Supports

1 study

38

Study: Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials.

This study provides evidence supporting the claim.

Contradicts

0 studies

0

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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