Taking L-arginine pills in these amounts doesn’t raise the levels of L-arginine or related molecules in your blood or urine, because your body breaks them down too quickly before they can get into...
Strongly contradicted
Multiple high-quality studies challenge this claim.
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Taking L-arginine pills in these amounts doesn’t raise the levels of L-arginine or related molecules in your blood or urine, because your body breaks them down too quickly before they can get into...
See the technical phrasing
Oral L-arginine supplementation at doses of 1.6 g twice daily or 1.0 g three times daily does not significantly increase plasma L-arginine concentration, urinary nitrate, or cGMP levels compared to placebo in healthy adults, due to extensive presystemic metabolism.
What the research says
Supports
0 studies
Contradicts
1 study
Study: Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
This study provides evidence contradicting the claim.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies