Taking NMN supplements for up to 3 months doesn’t seem to help improve blood sugar or cholesterol levels in healthy older adults.

What we've found so far is that short-term NMN supplementation does not appear to improve blood sugar or cholesterol levels in healthy middle-aged and older adults. Our analysis of the available evidence supports this observation. We analyzed 45 studies that looked at the effects of NMN supplements taken for up to three months in healthy older adults [1]. In all of these studies, researchers measured markers of blood sugar control and cholesterol levels. The results consistently showed no meaningful changes in these markers after NMN supplementation [1]. This means that, based on what we've reviewed so far, taking NMN for a few months doesn’t lead to improvements in blood sugar or cholesterol for people who are already healthy. It’s important to note that all 45 pieces of evidence point in the same direction—there are no studies in this analysis that show a benefit for these outcomes [1]. The evidence we've reviewed leans toward no effect, at least over the short term and in individuals without existing metabolic issues. We don’t yet know whether longer use of NMN, or use in people with elevated blood sugar or cholesterol, might lead to different results. Our current analysis only covers healthy adults and supplementation periods of up to three months. As always, new evidence could change our understanding over time. Practical takeaway: If you're a healthy middle-aged or older adult hoping to improve blood sugar or cholesterol with NMN, the evidence we’ve reviewed so far suggests this is unlikely to happen within the first few months of use.