Taking NMN pills every day for up to 12 weeks doesn’t seem to change weight, blood pressure, or liver health in middle-aged or older people.

What we've found so far is that taking NMN supplements daily for up to 12 weeks does not appear to have a noticeable effect on body weight, blood pressure, or liver health in middle-aged and older adults [1]. Our analysis of the available research shows this pattern across the evidence we’ve reviewed. We looked at 45.0 studies or assertions, all of which support the idea that NMN supplementation over this time frame does not lead to changes in these health markers [1]. There were no studies in our review that showed a clear effect on weight, blood pressure, or liver enzymes. This means that, based on what we've seen so far, people taking NMN for up to 12 weeks are not likely to see shifts in their BMI, blood pressure readings, or standard indicators of liver function. It’s important to note that all the data we’ve analyzed so far covers a relatively short period—up to 12 weeks. We don’t yet have enough evidence to say what might happen if someone takes NMN for a longer time. Also, the findings don’t rule out effects on other aspects of health, just these specific ones. Our current analysis shows the evidence leans toward no effect on BMI, blood pressure, or liver enzymes in this population over this duration. However, since our understanding is based on what’s been studied to date, future research could add new insights. Practical takeaway: If you're taking NMN for 12 weeks or less, don’t expect changes in your weight, blood pressure, or liver test results based on what we know right now.