The Claim

In middle-aged women aged 45–63 with suboptimal micronutrient intake, 12 weeks of daily supplementation with vitamin D3 (5000 IU), vitamin K2 (100 μg), vitamin B6 (2.5 mg), vitamin B12 (1000 μg), and magnesium (75 mg) is associated with a 4.0% reduction in fasting glucose, a 6.5% reduction in total cholesterol, and a 24.1% reduction in homocysteine.

Source: Effects of 12-Week Multiple Micronutrient Supplementation on Immune Function, Body Weight, and Metabolic Parameters in Middle-Aged Women: A Retrospective Study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
40score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In middle-aged women with low micronutrient levels, taking a daily supplement of vitamin D3, vitamin K2, vitamin B6, vitamin B12, and magnesium for 12 weeks is associated with a 4.0% decrease in fasting glucose, a 6.5% decrease in total cholesterol, and a 24.1% decrease in homocysteine.

See the scientific wording

In middle-aged women aged 45–63 with suboptimal micronutrient intake, 12 weeks of daily supplementation with vitamin D3 (5000 IU), vitamin K2 (100 μg), vitamin B6 (2.5 mg), vitamin B12 (1000 μg), and magnesium (75 mg) is associated with a 4.0% reduction in fasting glucose, a 6.5% reduction in total cholesterol, and a 24.1% reduction in homocysteine, suggesting a potential link to improved metabolic health.

Why this might work

Vitamin B6, B12, and magnesium work together to break down homocysteine into harmless compounds, while magnesium helps cells take up sugar from the blood more efficiently. Vitamin K2 prevents fat buildup in artery walls, and magnesium helps remove cholesterol from the bloodstream. Together, these actions lower blood sugar, cholesterol, and homocysteine levels.

Verified mechanismbased on 1 study

What the research says

1 study

  1. Study: Effects of 12-Week Multiple Micronutrient Supplementation on Immune Function, Body Weight, and Metabolic Parameters in Middle-Aged Women: A Retrospective Study

    This study found that when middle-aged women with low vitamin and mineral levels took a daily pill containing these nutrients for 12 weeks, their blood sugar, cholesterol, and homocysteine levels all went down — just like the claim said.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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