The Study
Effects of 12-Week Multiple Micronutrient Supplementation on Immune Function, Body Weight, and Metabolic Parameters in Middle-Aged Women: A Retrospective Study
This study watched what happened to 52 women after they took a vitamin pill for 12 weeks, and noticed they felt better or had healthier numbers. But we don’t know if the pills caused it—maybe they ate better or walked more. It’s like noticing your phone battery lasts longer after you turn off apps—you can’t be sure it was the apps or just that you used your phone less.
Analysis score
Maximum 44 for a cross-sectional study.
Where the score came from
A small group of women took a daily pill with five vitamins and magnesium for 12 weeks, and their blood tests and body measurements got better.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 540 / 100
Quality score
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1These changes suggest better immunity, less inflammation, and improved metabolism — which could mean lower risk of infections, heart disease, and weight-related issues.
- 2IgG went up 15.3%, IgA up 25%, CRP down 37.1%, weight down 1.4 kg, body fat down 1.2%, waist down 1.5 cm, homocysteine down 24.1%, fasting glucose down 4.0%, total cholesterol down 6.5%.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Cureus
Year
2025
Authors
Y. Sun
Related Content
Claims (10)
Taking dietary supplements restores essential nutrient levels in people who eat modern diets, and this restoration restores normal physiological function.
Taking dietary supplements restores missing micronutrients from inadequate food intake and maintains normal bodily functions.
In middle-aged women with low micronutrient levels, taking a daily supplement of vitamin D3, vitamin K2, vitamin B6, vitamin B12, and magnesium for twelve weeks is associated with lower fasting glucose, lower total cholesterol, and lower homocysteine levels.
In middle-aged women with low micronutrient levels, taking a daily supplement of vitamin D3, vitamin K2, vitamin B6, vitamin B12, and magnesium for twelve weeks is linked to lower LDL cholesterol without affecting HDL cholesterol or triglycerides.
In middle-aged women with low micronutrient levels, taking a daily supplement of vitamin D3, vitamin K2, vitamin B6, vitamin B12, and magnesium for 12 weeks is associated with a 4.0% decrease in fasting glucose, a 6.5% decrease in total cholesterol, and a 24.1% decrease in homocysteine.
Among middle-aged women with low micronutrient levels, taking a daily supplement of vitamin D3, vitamin K2, vitamin B6, vitamin B12, and magnesium for 12 weeks is linked to a 1.4 kg decrease in body weight, a 1.2% drop in body fat percentage, and a 1.5 cm reduction in waist circumference, with no change in lean mass.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.