A medicine called tesamorelin tricks the brain into making more of its own growth hormone, instead of giving the hormone directly.

Tesamorelin makes the body produce more of its own growth hormone naturally, which helps reduce belly fat—when the drug is stopped, the fat comes back, proving it’s not a fake boost but a real, temporary signal from the body.

Tesamorelin helped the body make more of its own growth hormone, which then led to higher levels of a related protein (IGF-I), showing it worked the way the body naturally does.

Tesamorelin is a drug that tricks the brain into releasing growth hormone naturally, and this study shows it works in people with HIV — meaning it makes the body produce growth hormone in a normal, pulsing way, not just by forcing it out.