Tesamorelin only targets dangerous belly fat in HIV patients, leaving other fat stores like arms and legs unchanged.

The drug doesn’t make you lose fat from your skin or your arms and legs — it only targets the fat deep inside your belly, which is the kind that’s most dangerous.

A hormone treatment called tesamorelin doesn't change the fat under the skin in people with HIV who have excess belly fat after six months of treatment.

Continuing tesamorelin for a full year helps HIV patients with belly fat lose nearly 18% of their dangerous internal belly fat, with no loss of benefit over time.

If HIV patients stop taking the injection, the belly fat they lost comes right back quickly.

The drug shrinks the fat around the torso and makes the waist smaller, but doesn’t change the fat on the arms, legs, or just under the skin — meaning it targets only the dangerous internal fat.