Scientists gave mice or other lab animals food with three different supplements, but accidentally gave much smaller amounts than they planned. Even with less supplement, two of them (astaxanthin and meclizine) still made the animals live longer.

13

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Against

Evidence from Studies

Supporting (1)

13

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13

Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

Cohort Study

Animal

2024 Feb

The study fed mice three different drugs in their food, but the actual amounts they got were lower than planned (less than half for two of them). Even with these lower doses, two of the drugs (astaxanthin and meclizine) still made the male mice live longer. The third drug (dimethyl fumarate) didn't work, likely because the dose was too low.

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

Score: 13

DOI: 10.1007/s11357-023-01011-0

Similar Assertions

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