The amount of oral bacteria that convert nitrates to nitrites doesn't seem to be related to whether people have prediabetes or high blood pressure.

Scientific Claim

No significant association was found between nitrate-reducing oral bacteria and prediabetes prevalence or hypertension prevalence in adults without diabetes.

Original Statement

“No associations were observed with prediabetes mellitus and hypertension.”

From study:Association Between Nitrate‐Reducing Oral Bacteria and Cardiometabolic Outcomes: Results From ORIGINS

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study is observational and cross-sectional, so 'no association' is the correct way to state this finding. The claim accurately reflects the statistical results without implying causation.

Evidence from Studies

Supporting (1)

Association Between Nitrate‐Reducing Oral Bacteria and Cardiometabolic Outcomes: Results From ORIGINS

Cross-Sectional Study

Human

2019 Dec 3

Contradicting (0)

No contradicting evidence found

Source Study

Association Between Nitrate‐Reducing Oral Bacteria and Cardiometabolic Outcomes: Results From ORIGINS

Score: 53

DOI: 10.1161/JAHA.119.013324

Similar Assertions

People with more oral bacteria that convert nitrates to nitrites tend to have lower blood sugar levels.

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People with more oral bacteria that convert nitrates to nitrites tend to have better insulin sensitivity, meaning their bodies handle sugar better.

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Even after accounting for many other factors that could affect insulin sensitivity, the link between oral bacteria that convert nitrates to nitrites and better insulin sensitivity still holds true.

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People with more oral bacteria that convert nitrates to nitrites tend to have lower blood pressure, but only if they don't already have high blood pressure.

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The small blood pressure increase from using the special mouthwash was similar in size to what's known to increase the risk of heart disease and stroke.

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