The blood pressure increase from using the special mouthwash happened both during the day and at night, with the diastolic pressure going up more during the day.

Scientific Claim

In healthy young adults, the blood pressure increase from disrupting oral nitrate-reducing bacteria was observed during both daytime and nighttime periods, with daytime diastolic blood pressure showing a more pronounced increase.

Original Statement

“Separation of ABPM data into daytime and nighttime means demonstrates that daytime ambulatory SBP and DBP were increased post-mouthwash (ΔSBP 2.9 ± 0.9 mm Hg, p = 0.004, and ΔDBP 3.0 ± 0.8 mm Hg, p = 0.002, respectively), whereas mouthwash increased only nighttime SBP (ΔSBP 2.2 ± 0.9, p = 0.022) and not DBP.”

From study:Physiological role for nitrate-reducing oral bacteria in blood pressure control

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study design supports describing the time-of-day patterns of blood pressure changes. The language 'was observed' appropriately reflects the observed pattern without implying causation.

More Accurate Statement

“In healthy young adults, the blood pressure increase following disruption of oral nitrate-reducing bacteria was observed during both daytime and nighttime periods, with daytime diastolic blood pressure showing a more pronounced increase.”

Evidence from Studies

Supporting (1)

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Randomized Controlled Trial

Human

2013 Feb

Contradicting (0)

No contradicting evidence found

Source Study

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Score: 45

DOI: 10.1016/j.freeradbiomed.2012.11.013

Similar Assertions

The blood pressure increase from using the special mouthwash was the same whether measured at the doctor's office, at home, or with a 24-hour monitor.

93%

When people used the special mouthwash, their blood pressure went up but their heart rate didn't change, which suggests the effect is specific to blood pressure regulation.

90%

Even when people ate a diet low in nitrate, using the special mouthwash still increased their blood pressure, which suggests the effect comes from the body's own nitrate recycling process.

89%

When mouth bacteria are disrupted, blood pressure goes up regardless of how it's measured - whether at the doctor's office, at home, or with a 24-hour monitor.

89%

The small blood pressure increase from using the special mouthwash was similar in size to what's known to increase the risk of heart disease and stroke.

88%