Analysis Version
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History
Back to Study: Physiological role for nitrate-reducing oral bacte...
descriptive
45
Pro
0
Against

When people used the special mouthwash, their blood pressure went up but their heart rate didn't change, which suggests the effect is specific to blood pressure regulation.

Scientific Claim

In healthy young adults, the blood pressure increase from disrupting oral nitrate-reducing bacteria was not accompanied by changes in heart rate, suggesting the effect is specific to blood pressure regulation.

Original Statement

“There were no changes in HR as estimated using all three distinct techniques: clinic ΔHR 2.0 ± 1.7 bpm, p = 0.25; home ΔHR 1.3 ± 1.0 bpm, p = 0.18; and ambulatory ΔHR 2.0 ± 1.4 bpm, p = 0.17 (data not shown).”

From study:Physiological role for nitrate-reducing oral bacteria in blood pressure control

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study design supports describing the lack of change in heart rate alongside blood pressure changes. The language 'was not accompanied by changes' appropriately reflects the observed pattern without implying causation.

More Accurate Statement

“In healthy young adults, the blood pressure increase following disruption of oral nitrate-reducing bacteria was not associated with changes in heart rate, suggesting the effect is specific to blood pressure regulation.”

Evidence from Studies

Supporting (1)

45
45

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Randomized Controlled Trial
Human
2013 Feb

Contradicting (0)

0
No contradicting evidence found

Source Study

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Score: 45
DOI: 10.1016/j.freeradbiomed.2012.11.013

Similar Assertions

The small blood pressure increase from using the special mouthwash was similar in size to what's known to increase the risk of heart disease and stroke.

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93%

Even when people ate a diet low in nitrate, using the special mouthwash still increased their blood pressure, which suggests the effect comes from the body's own nitrate recycling process.

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91%

When mouth bacteria are disrupted, blood pressure goes up regardless of how it's measured - whether at the doctor's office, at home, or with a 24-hour monitor.

45
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90%

The blood pressure increase from using the special mouthwash was the same whether measured at the doctor's office, at home, or with a 24-hour monitor.

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90%

The blood pressure increase from using the special mouthwash happened both during the day and at night, with the diastolic pressure going up more during the day.

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0
90%