The gene for the GLP-1 receptor isn't found in certain heart cells, so those cells probably aren't the main places where this receptor works in the human heart when things are normal.

Scientists found the genetic instructions for a certain receptor in the heart's natural pacemaker, which might mean that a hormone involved in blood sugar control could directly affect how fast your heart beats.

We know the heart has the genetic instructions for a certain protein (GLP-1R), but we can't yet tell which exact heart cells actually make it because our tools aren't sensitive enough to see it clearly.

The heart has the same kind of genetic message for the GLP-1 receptor as the pancreas, which means the heart might respond to GLP-1 signals—even though we're not sure yet if that message actually turns into working proteins there.

In the human heart, the GLP-1 receptor is more active than similar receptors, and one of them isn't detectable at all in a key heart chamber — suggesting the heart may respond more to GLP-1-based signals.