The gene for the GLP-1 receptor isn't found in certain heart cells, so those cells probably aren't the main places where this receptor works in the human heart when things are normal.

56

Pro

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Against

Evidence from Studies

Supporting (1)

56

Community contributions welcome

56

GLP-1 Receptor Expression Within the Human Heart

Cross-Sectional Study

Human

2018 Apr 1

The study looked for GLP-1 receptor messages (mRNA) in specific heart cells and didn't find them in fibroblasts or blood vessel cells, which supports the idea that these cells don't make this receptor in the human heart.

Contradicting (0)

0

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

GLP-1 Receptor Expression Within the Human Heart

Score: 56

DOI: 10.1210/en.2018-00004

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