The cellular cleanup system called the proteasome is more active in people having a heart attack compared to those with stable heart disease, which might be related to the body's response to the...

In people with stable heart disease, when the proteasome (cellular cleanup system) is more active, there's less PLIN2 protein present, but this relationship doesn't hold for people having a heart attack, suggesting different ways PLIN2 is regulated in these two conditions.

In people with stable heart disease, when the proteasome (a cellular cleanup system) is more active, there's less PLIN2 protein present, but this relationship doesn't hold for people having a heart attack.

In people having a heart attack, PLIN2 protein stays high even though the cellular cleanup system (proteasome) is more active, suggesting there might be special reasons why PLIN2 isn't being broken down properly during a heart attack.