The enzyme that makes blood pressure hormones increased in both kidneys of mice with high blood pressure, and PRO20 didn't stop this increase.

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Pro

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Against

Evidence from Studies

Supporting (1)

11

Community contributions welcome

11

(Pro)renin Receptor Blockade Prevents Increases in Systolic Blood Pressure, Sodium Retention, and αENaC Protein Expression in the Kidney of 2K1C Goldblatt Mice

Randomized Controlled Trial

Animal

2025 Apr 28

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

(Pro)renin Receptor Blockade Prevents Increases in Systolic Blood Pressure, Sodium Retention, and αENaC Protein Expression in the Kidney of 2K1C Goldblatt Mice

Score: 11

DOI: 10.3390/ijms26094177

Similar Assertions

When given PRO20, mice with high blood pressure didn't show higher levels of a key blood pressure hormone in the non-clipped kidney.

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0

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