Doctors found that fat around the organs in women's bellies has more of certain proteins that handle stress hormones compared to the fat under the skin.

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Pro

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Against

Evidence from Studies

Supporting (1)

41

Community contributions welcome

41

Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue.

Cross-Sectional Study

Human

2010 Oct

Researchers took fat samples from two different locations in women's bellies during gynecological surgery and measured gene activity. They found that the fat inside the belly (omental) had higher activity of three specific genes (11β-HSD2, H6PDH, and GRα) compared to fat under the skin (subcutaneous), exactly matching what the claim says.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue.

Score: 41

DOI: 10.1016/j.jsbmb.2010.02.024

Similar Assertions

In women, higher levels of a specific enzyme (11β-HSD1) in fat tissue are linked to having more body fat, especially around the belly.

41

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In women who have fat stored around their internal organs (visceral obesity), the fat tissue produces more of a specific enzyme and hormone related to stress compared to women without this type of fat buildup.

41

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In women, a higher amount of a specific enzyme called H6PDH in the fat around the organs is linked to having less body fat overall.

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Scientists found that the activity of a specific gene (11β-HSD1) in belly fat can help predict how much belly fat a woman has, even after accounting for her total body fat, age, and whether she's gone through menopause.

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In Chinese adults, people with higher levels of a specific enzyme (11beta-HSD1) in their belly fat tend to also have higher body weight, as measured by BMI.

27

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