Scientists found the genetic instructions for a certain receptor in the heart's natural pacemaker, which might mean that a hormone involved in blood sugar control could directly affect how fast your heart beats.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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GLP-1 Receptor Expression Within the Human Heart

Cross-Sectional Study

Human

2018 Apr 1

The study found the genetic signal for the GLP-1 receptor in the heart's natural pacemaker, which supports the idea that this part of the heart could respond directly to GLP-1-related drugs.

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Source Study

GLP-1 Receptor Expression Within the Human Heart

Score: 56

DOI: 10.1210/en.2018-00004

Similar Assertions

The gene for the GLP-1 receptor isn't found in certain heart cells, so those cells probably aren't the main places where this receptor works in the human heart when things are normal.

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84%

We know the heart has the genetic instructions for a certain protein (GLP-1R), but we can't yet tell which exact heart cells actually make it because our tools aren't sensitive enough to see it clearly.

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81%

The heart has the same kind of genetic message for the GLP-1 receptor as the pancreas, which means the heart might respond to GLP-1 signals—even though we're not sure yet if that message actually turns into working proteins there.

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81%

In the human heart, the GLP-1 receptor is more active than similar receptors, and one of them isn't detectable at all in a key heart chamber — suggesting the heart may respond more to GLP-1-based signals.

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77%