If you push your muscles until they can't do another rep, you create more force per set—which can help if you're not doing many sets, but might hurt your progress if you're already doing a lot of work.
Evidence from Studies
Supporting (3)
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Effects of resistance training performed to repetition failure or non-failure on muscular strength and hypertrophy: A systematic review and meta-analysis
This study found that lifting until you can't do another rep doesn't help you get stronger or bigger more than stopping before failure — and if you're already doing a lot of reps, going to failure might even hurt your progress.
Acute effects of equated volume-load resistance training leading to muscular failure versus non-failure on neuromuscular performance
When people lift weights until they can't do another rep, their muscles get way more tired—even if they do the same total amount of work as someone who stops earlier. This means going to failure makes each set harder on your body, which helps if you're doing few sets, but hurts if you're already doing a lot.
Low-Load Resistance Training to Volitional Failure Induces Muscle Hypertrophy Similar to Volume-Matched, Velocity Fatigue
This study found that lifting light weights until you can't do another rep builds muscle just as well as doing more reps without going all the way to failure — meaning going to failure can make up for doing fewer total reps. It supports the idea that failure helps when you're not doing much volume.
Contradicting (1)
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The study found that lifting until you can't do another rep doesn't make your muscles grow more than stopping just before failure — as long as you do the same total amount of work. So, pushing to failure isn't needed, and might even make you more tired for no extra gain.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.