Going all the way to muscle burnout during weight training tires out your brain and nerves more than stopping just before total exhaustion.

If you lift weights until you literally can't do another rep, you'll feel more tired right after than if you stop a couple reps before failure — even if you're someone who regularly lifts weights.

Lifting weights until you can't do another rep leaves you much more tired during and after the workout than stopping a few reps short — even if both methods build muscle equally.

Your brain and how tired your body gets during weight training might affect how much your muscles grow — so it's not just about the muscles themselves.

Going all the way to muscle failure during weight training makes you way more tired—both mentally and physically—but doesn’t help you build more muscle than stopping just short, so it might not be worth the extra effort.

If you lift weights until you can't do another rep, or stop just before failure, your thigh muscles grow about the same amount after eight weeks — but stopping short feels less exhausting each time.