The Claim
Uric acid concentrations above 0.36 mmol/L in blood cause crystallization in joint tissues.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When uric acid levels in the blood exceed 0.36 mmol/L, crystals form in joint tissues.
See the scientific wording
Uric acid concentrations above 0.36 mmol/L in blood can lead to crystallization in joint tissues.
When there is too much uric acid in the blood, it forms sharp crystals in joints and other tissues. These crystals are recognized by immune cells, which swallow them and get damaged. This damage causes the cells to release signals that turn on a powerful inflammation system, leading to swelling, pain, and tissue injury.
What the research says
2 studiesStudy: Effect of Monosodium Urate Crystal Deposition on Atherosclerotic Carotid Plaques
When people have more uric acid in their blood, they’re more likely to have tiny crystals form in their body tissues — this study found that people with crystals had much higher uric acid levels than those without.
When there's too much uric acid in the blood—more than 0.36 mmol/L—it turns into sharp crystals that can get stuck in joints and cause pain, like in gout. The study says this happens right at that level.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 2 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.