Analysis Version
vnull
History
Back to Study: The comparative effect of propolis and chlorhexidi...
quantitative
67
Pro
0
Against

Using a bee resin mouthwash for a week doesn't change the types or numbers of bacteria that produce nitrite in the mouth.

Scientific Claim

Propolis mouthwash (2.5%) does not significantly alter the relative abundance of nitrite-producing species or nitrite-producing activity in the oral microbiome of healthy adults after 7 days of use.

Original Statement

“No significant differences in the relative abundance of NPS and NPA were observed in the PROP-M group.”

From study:The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

This is a randomized controlled trial with direct measurement of bacterial abundance and activity before and after intervention. The absence of statistically significant differences (p>0.05) supports definitive language for this specific finding.

Evidence from Studies

Supporting (1)

67
67

The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Randomized Controlled Trial
Human
2025

Contradicting (0)

0
No contradicting evidence found

Source Study

The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Score: 67
DOI: 10.1080/20002297.2024.2439636

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