The Claim

In 19 adults with elevated cardiometabolic risk, a single acute dose of 5g TOTUM-63 was followed by a statistically significant reduction in postprandial glucose peak (p=0.03) and GIP AUC (p=0.01), suggesting a potential association between this supplement and acute modulation of post-meal glucose and incretin responses.

Source: 725-P: TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
20score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

A single 5g dose of TOTUM-63 reduced the peak blood glucose level and the total exposure to the hormone GIP after a meal in 19 adults with elevated cardiometabolic risk.

See the scientific wording

In 19 adults with elevated cardiometabolic risk, a single acute dose of 5g TOTUM-63 was followed by a statistically significant reduction in postprandial glucose peak (p=0.03) and GIP AUC (p=0.01), suggesting a potential association between this supplement and acute modulation of post-meal glucose and incretin responses.

Why this might work

Plant compounds in the supplement feed beneficial gut bacteria, which produce substances that strengthen the gut lining. This reduces inflammation and changes how gut cells release hormones, leading to less GIP being released after eating, which in turn lowers the spike in blood sugar.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: 725-P: TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk

    When 19 people at risk for diabetes took one dose of this plant-based supplement, their blood sugar spike after eating went down, and a hormone called GIP that helps release insulin also dropped—exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.