The Claim
Daily oral desogestrel at doses of 75 to 300 micrograms combined with a 300 mg testosterone pellet for 8 weeks is associated with dose-dependent suppression of sperm concentration in healthy men, with the highest dose achieving severe oligozoospermia in seven out of ten participants.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In healthy men, taking daily oral desogestrel at 75 to 300 micrograms along with a 300 mg testosterone pellet for 8 weeks reduces sperm concentration in a dose-dependent manner, and the highest dose caused severe reduction in sperm count in seven of ten participants.
See the scientific wording
Daily oral desogestrel at doses of 75 to 300 micrograms combined with a 300 mg testosterone pellet for 8 weeks is associated with dose-dependent suppression of sperm concentration in healthy men, with the highest dose achieving severe oligozoospermia in seven out of ten participants.
A hormone pill and a testosterone implant together signal the brain to stop producing signals that tell the testes to make sperm. Without those signals, the testes stop producing testosterone inside themselves and cannot support sperm development, leading to very low or no sperm in semen.
What the research says
1 studyWhen men took a higher dose of a hormone pill along with a testosterone implant for 8 weeks, most of them had very few or no sperm left — and the higher the pill dose, the lower their sperm count got. This shows the treatment works as claimed.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.