The Claim

In obese adults following a 500-calorie-per-day restricted diet, daily supplementation with 20 grams of Prolibra™ whey protein (containing high leucine, bioactive peptides, and milk calcium) before breakfast and dinner for 12 weeks results in significantly greater fat loss (2.81 kg) and significantly less lean muscle loss (0.75 kg) compared to an isocaloric control beverage, yielding a fat-to-lean-mass-loss ratio of 3.75:1 versus 1.05:1 in controls.

Source: A whey-protein supplement increases fat loss and spares lean muscle in obese subjects: a randomized human clinical study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
71score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Obese adults on a 500-calorie-per-day diet who take 20 grams of Prolibra™ whey protein before breakfast and dinner for 12 weeks lose 2.81 kg of fat and 0.75 kg of muscle, while those who take a control beverage lose 1.62 kg of fat and 1.55 kg of muscle.

See the scientific wording

In obese adults following a 500-calorie-per-day restricted diet, daily supplementation with 20 grams of Prolibra™ whey protein (containing high leucine, bioactive peptides, and milk calcium) before breakfast and dinner leads to significantly greater fat loss (2.81 kg vs. 1.62 kg) and significantly less lean muscle loss (0.75 kg vs. 1.55 kg) over 12 weeks compared to an isocaloric control beverage, resulting in a 3.75:1 ratio of fat to lean mass loss versus 1.05:1 in controls.

Why this might work

When a person eats less food, a special protein in the supplement triggers muscle cells to build and keep more muscle by turning on a key growth signal. At the same time, it lowers two stress hormones that make the body store fat and break down muscle. This causes the body to burn fat for energy instead of muscle, so more fat is lost and less muscle is lost.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: A whey-protein supplement increases fat loss and spares lean muscle in obese subjects: a randomized human clinical study

    When obese people eat less, taking this special whey protein shake twice a day helps them lose more fat and keep more muscle than taking a plain shake with the same calories.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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